Infections May Cause Arterial Inflammation, Atherosclerosis, Myocarditis and Cardiovascular Disease

نویسندگان

چکیده

Effective prevention and treatment of atherosclerosis cardiovascular disease (CVD), the commonest cause death in most countries, is still lacking. For many years we have studied cholesterol hypothesis found that there are contradictions to this hypothesis. instance, no trial has shown exposure response; lipid values not associated with degree atherosclerosis, people high LDL-C live just as long or longer than low LDL-C. These facts together observation inflammation a common finding atherosclerotic arteries probably contributed CVD may be caused by inflammation. However, several trials anti-inflammatory drugs such increases risk CVD. Therefore, relevant whether it infections which because human observations animal experiments accordance idea. As cholesterol-lowering ineffective serious side effects, believe future research should elucidate importance etiology A method would perform blood culture on all patients an acute AMI if positive, treat patient appropriate antibiotic.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

An inflammation test that may predict cardiovascular disease

In 2010, Ingela Schnittger, MD, a cardiologist at the School of Medicine, sat in her lab examining the echocardiogram of a young man who came to the heart clinic at Stanford Health Care complaining of chest pain. She spotted a curious motion of the heart on the computer screen, one that she’d seen before while examining these kinds of diagnostic tests. “All of the sudden I had this flashback,” ...

متن کامل

Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis

Objective(s): Myocarditis is characterized by inflammatory cell infiltration in myocardial stroma. Attenuation of tumor necrosis factor (TNF)-α and interleukin (IL)-1β is a reliable mark for improving the prognosis. Protein kinase B (Akt) plays an important role in the development and progression of myocarditis. The specific role of the natural inhibitor of Akt, Deguel...

متن کامل

Inflammation and cardiovascular disease

There now exists overwhelming evidence supporting the inflammatory hypothesis of atherosclerotic vascular disease. Cellular interactions between leukocytes, platelets and endothelial cells are critical in the initiation and progression of atherosclerotic disease. Acute coronary syndromes, namely unstable angina and acute myocardial infarction, and thromboembolic stroke represent acute unstable ...

متن کامل

Immunity, atherosclerosis and cardiovascular disease

Atherosclerosis, the major cause of cardiovascular disease (CVD), is a chronic inflammatory condition with immune competent cells in lesions producing mainly pro-inflammatory cytokines. Dead cells and oxidized forms of low density lipoproteins (oxLDL) are abundant. The major direct cause of CVD appears to be rupture of atherosclerotic plaques. oxLDL has proinflammatory and immune-stimulatory pr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Medical research archives

سال: 2023

ISSN: ['2375-1916', '2375-1924']

DOI: https://doi.org/10.18103/mra.v11i5.3866